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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-Ras-PDEδ-IN-99
PDEδ-IN-99

Chemical Structure : PDEδ-IN-99

CAS No.: 1841464-21-8

PDEδ-IN-99 (K-Ras-PDEδ inhibitor)

货号: PC-61995Not For Human Use, Lab Use Only.

PDEδ-IN-99 is a novel potent K-Ras-PDEδ inhibitor that binds to the farnesyl binding pocket of PDEδ (PDE6D) with Kd of 8 nM.

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10 mg ¥3580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PDEδ-IN-99 is a novel potent K-Ras-PDEδ inhibitor that binds to the farnesyl binding pocket of PDEδ (PDE6D) with Kd of 8 nM.

物理化学性质&存储条件

分子量 447.514
分子式 C25H26FN5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-fluorophenethyl)-4-(4-methyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)butanamide

参考文献

1. Murarka S, et al. Chemistry. 2017 May 2;23(25):6083-6093.

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