PDE3B inhibitor 18f | PDE3B inhibitor | Probechem Biochemicals

Chemical Structure : PDE3B inhibitor 18f

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货号: PC-25899Not For Human Use, Lab Use Only.

PDE3B inhibitor 18f (PDE3B-IN-3) is a potent, subtype selective PDE3B inhibitor with IC50 of 4.5 nM, >30-fold selective over PDE3A (IC50=150 nM).

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PDE3B inhibitor 18f (PDE3B-IN-3) is a potent, subtype selective PDE3B inhibitor with IC50 of 4.5 nM, >30-fold selective over PDE3A (IC50=150 nM).

分子量	450.47
分子式	C24H23FN4O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(2-fluoro-4-((2-(3-nitrobenzyl)-3-oxocyclohex-1-en-1-yl)amino)phenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

1. Edmondson SD, et al. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3983-7.