PDE1 inhibitor 3f

Chemical Structure : PDE1 inhibitor 3f

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货号: PC-23410Not For Human Use, Lab Use Only.

PDE1 inhibitor 3f is a potent, selective PDE1 inhibitor with IC50 of 11 nM, >24-fold selectivity over other PDEs, shows antifibrotic effects in vivo and in vitro.

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250 mg		Get quote

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PDE1 inhibitor 3f is a potent, selective PDE1 inhibitor with IC50 of 11 nM, >24-fold selectivity over other PDEs, shows antifibrotic effects in vivo and in vitro.

物理化学性质&存储条件

分子量	408.32
分子式	C17H11Cl2N3OS2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((1-(3-Chlorophenyl)ethyl)thio)-4-(5-chlorothiophen-2-yl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile

参考文献

1. Jiang MY, et al. J Med Chem. 2024 Nov 15. doi: 10.1021/acs.jmedchem.4c01533.