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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-PDE12-IN-3
PDE12-IN-3

Chemical Structure : PDE12-IN-3

CAS No.: 1803357-22-3

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PDE12-IN-3

货号: PC-60875Not For Human Use, Lab Use Only.

PDE12-IN-3 is a potent phosphodiesterase 12 (PDE12) with Ki of 17.5 nM, with no activity for related enzyme CNOT6 (Ki>10 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    PDE12-IN-3 is a potent phosphodiesterase 12 (PDE12) with Ki of 17.5 nM, with no activity for related enzyme CNOT6 (Ki>10 uM).
    PDE12-IN-3 exhibits antiviral activity comparable with the effects observed with PDE12 gene inactivation.

    物理化学性质&存储条件

    分子量 491.551
    分子式 C29H25N5O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    3-(6-(3-(hydroxymethyl)-2-phenylmorpholine-4-carbonyl)-1-methyl-1H-benzo[d]imidazol-2-yl)-1H-indole-6-carbonitrile

    参考文献

    1. Wood ER, et al. J Biol Chem. 2015 Aug 7;290(32):19681-96.

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