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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Matrix Metalloproteinase (MMP)-PD166793
PD166793

Chemical Structure : PD166793

CAS No.: 199850-67-4

PD166793 (PD-166793)

货号: PC-22480Not For Human Use, Lab Use Only.

PD166793 (PD-166793 ) is a selective, orally active broad spectrum inhibitor of MMPs with IC50 of 4, 7, and 8 nM for MMP-2, MMP-3 and MMP-13, inhibits MMP-1, MMP-7 and MMP-9 with IC50 of 6-8 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PD166793 (PD-166793 ) is a selective, orally active broad spectrum inhibitor of MMPs with IC50 of 4, 7, and 8 nM for MMP-2, MMP-3 and MMP-13, inhibits MMP-1, MMP-7 and MMP-9 with IC50 of 6-8 uM.

物理化学性质&存储条件

分子量 412.30
分子式 C17H18BrNO4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

((4'-bromo-[1,1'-biphenyl]-4-yl)sulfonyl)-L-valine

参考文献

1. McElmurray JH 3rd, et al. J Pharmacol Exp Ther. 1999 Nov;291(2):799-811.

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