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首页-小分子抑制剂&激动剂-GPCR-Angiotensin Receptor-PD 123319 ditrifluoroacetate
PD 123319 ditrifluoroacetate

Chemical Structure : PD 123319 ditrifluoroacetate

CAS No.: 136676-91-0

PD 123319 ditrifluoroacetate (PD123319 ditrifluoroacetate, PD123,319 ditrifluoroacetate)

货号: PC-42495Not For Human Use, Lab Use Only.

PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin II type 2 receptor (AT2 receptor) antagonist with IC50 of 34 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PD 123319 ditrifluoroacetate is a potent, selective, non-peptide angiotensin II type 2 receptor (AT2 receptor) antagonist with IC50 of 34 nM.

物理化学性质&存储条件

分子量 736.6575
分子式 C35H34F6N4O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

H2O: ≥ 36 mg/mL

Chemical Name/SMILES

1H-Imidazo[4,5-c]pyridine-6-carboxylic acid, 1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-, (6S)-, 2,2,2-trifluoroacetate (1:2)

参考文献

1. Blankley CJ, et al. J Med Chem. 1991 Nov;34(11):3248-60.

2. Keiser JA, et al. J Pharmacol Exp Ther. 1992 Sep;262(3):1154-60.

3. Macari D, et al. Eur J Pharmacol. 1993 Nov 2;249(1):85-93.

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