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首页-小分子抑制剂&激动剂-Others-Other Targets-PCiB-2
PCiB-2

Chemical Structure : PCiB-2

CAS No.: 731816-59-4

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PCiB-2

货号: PC-21864Not For Human Use, Lab Use Only.

PCiB-2 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 2.0 uM, inhibits the phosphatidylethanolamine (PE) methyltransferase activity of Cho2, induces mitochondrial division.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PCiB-2 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 2.0 uM, inhibits the phosphatidylethanolamine (PE) methyltransferase activity of Cho2, induces mitochondrial division.

物理化学性质&存储条件

分子量 388.26
分子式 C15H15Cl2N3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(3-(3,4-dichlorophenyl)ureido)-N,N-dimethylbenzenesulfonamide

参考文献

1. Hiroya Shiino, et al. iScience. 2024 Feb 10;27(3):109189.

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