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首页-小分子抑制剂&激动剂-Others-Other Targets-PCiB-1
PCiB-1

Chemical Structure : PCiB-1

CAS No.: 626219-17-8

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PCiB-1

货号: PC-21863Not For Human Use, Lab Use Only.

PCiB-1 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 7.0 uM, inhibits phosphatidylethanolamine (PE) transport from mitochondria to the endoplasmic reticulum (ER), induces mitochondrial division.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PCiB-1 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 7.0 uM, inhibits phosphatidylethanolamine (PE) transport from mitochondria to the endoplasmic reticulum (ER), induces mitochondrial division.

物理化学性质&存储条件

分子量 316.34
分子式 C11H10F2N4OS2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(2,4-difluorophenyl)-3-(3-(ethylthio)-1,2,4-thiadiazol-5-yl)urea

参考文献

1. Hiroya Shiino, et al. iScience. 2024 Feb 10;27(3):109189.

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