PCW-A1001 | FLT3 D835Y inhibitor | Probechem Biochemicals

Chemical Structure : PCW-A1001

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PCW-A1001 (FLT3 D835Y mutant inhibitor)

货号: PC-20211Not For Human Use, Lab Use Only.

PCW-A1001 is a potent, selective inhibitor of FLT-3 (D835Y) mutant with IC50 of 764 nM, weakly inhibits WT FLT-3 with IC50 of 2.54 uM.

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生物&药学活性

PCW-A1001 is a potent, selective inhibitor of FLT-3 (D835Y) mutant with IC50 of 764 nM, weakly inhibits WT FLT-3 with IC50 of 2.54 uM.
PCW-A1001 inhibited the proliferation of MV4-11 cells with IC50 of 1.98 uM.

物理化学性质&存储条件

分子量	394.52
分子式	C23H30N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(tert-butyl)-N-(4-carbamoyl-3-(piperidin-3-ylamino)phenyl)benzamide

参考文献

1. Seong Hun Jang, et al. Front Mol Biosci. 2022 Nov 25;9:1072028.

PCW-A1001 (FLT3 D835Y mutant inhibitor)

生物&药学活性

物理化学性质&存储条件

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PCW-A1001 (FLT3 D835Y mutant inhibitor)

生物&药学活性

物理化学性质&存储条件

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