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首页-小分子抑制剂&激动剂-Tyrosine Kinase-BTK-PCI-29732
PCI-29732

Chemical Structure : PCI-29732

CAS No.: 330786-25-9

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PCI-29732 (PCI29732;PCI 29732)

货号: PC-45400Not For Human Use, Lab Use Only.

APCI-29732 is a potent, selective and irreversible Btk inhibitor with biochemical Ki of 8.2 nM.

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5 mg ￥880 In stock
10 mg ￥1280 In stock
25 mg ￥1980 In stock
50 mg ￥3280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PCI-29732 is a potent, selective and irreversible Btk inhibitor with biochemical Ki of 8.2 nM.
PCI-29732 also inhibits Lck and Lyn with Ki of 4.6 and 2.5 nM, respectively.

物理化学性质&存储条件

分子量 371.435
分子式 C22H21N5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 53 mg/mL
Chemical Name/SMILES

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-cyclopentyl-3-(4-phenoxyphenyl)-

参考文献

1. Pan Z, et al. ChemMedChem. 2007 Jan;2(1):58-61.

2. Honigberg LA, et al. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.

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