PC190723 | FtsZ inhibitor | Probechem Biochemicals

Chemical Structure : PC190723

CAS No.: 951120-33-5

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PC190723 (PC 190723)

货号: PC-47012Not For Human Use, Lab Use Only.

PC190723 is a small molecule inhibitor of FtsZ with potent and selective anti-staphylococcal activity, inhibits FtsZ and prevents cell division.

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5 mg	￥2980	In stock
10 mg	￥4580	In stock
25 mg	￥7580	In stock
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100 mg		Get quote

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生物&药学活性

PC190723 is a small molecule inhibitor of FtsZ with potent and selective anti-staphylococcal activity, inhibits FtsZ and prevents cell division.
PC190723 has potent and selective in vitro bactericidal activity against staphylococci, including methicillin- and multi-drug-resistant Staphylococcus aureus.
PC190723 is efficacious in an in vivo model of infection, curing mice infected with a lethal dose of S. aureus.
PC190723 acts synergistically with β-lactam antibiotics in vitro and in vivo.

物理化学性质&存储条件

分子量	355.744
分子式	C14H8ClF2N3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-[(6-Chlorothiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide

参考文献

1. Sedelnikova SE, et al. Science. 2008 Sep 19;321(5896):1673-5.

2. Andreu JM, et al. J Biol Chem. 2010 May 7;285(19):14239-46.

3. Tan CM, et al. Sci Transl Med. 2012 Mar 21;4(126):126ra35.

PC190723 (PC 190723)

生物&药学活性

物理化学性质&存储条件

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PC190723 (PC 190723)

生物&药学活性

物理化学性质&存储条件

参考文献

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