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首页-小分子抑制剂&激动剂-Epigenetics-Bromodomain-PBRM1-BD2 inhibitor 34
PBRM1-BD2 inhibitor 34

Chemical Structure : PBRM1-BD2 inhibitor 34

CAS No.: 2819989-75-6

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PBRM1-BD2 inhibitor 34 (PBRM1-BD2-IN-8)

货号: PC-25803Not For Human Use, Lab Use Only.

PBRM1-BD2 inhibitor 34 (PBRM1-BD2-IN-8) is a potent, selective PBRM1 bromodomain inhibitor with Kd of4.4 uM, IC50 of 0.16 uM for PBRM1-BD2, shows promising inhibition toward PBRM1-dependent prostate cancer cell line LNCaP with IC50 of 9 uM.

规格 价格 库存 数量
5 mg ￥1280 In stock
10 mg ￥1980 In stock
25 mg ￥3580 In stock
50 mg Get quote
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

PBRM1-BD2 inhibitor 34 (PBRM1-BD2-IN-8) is a potent, selective PBRM1 bromodomain inhibitor with Kd of4.4 uM, IC50 of 0.16 uM for PBRM1-BD2, shows promising inhibition toward PBRM1-dependent prostate cancer cell line LNCaP with IC50 of 9 uM.

物理化学性质&存储条件

分子量 317.19
分子式 C15H13BrN2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-Bromo-2-(m-tolyl)-2,3-dihydroquinazolin-4(1H)-one

参考文献

1. Shishodia S, et al. J Med Chem. 2022 Oct 27;65(20):13714-13735.

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