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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Arginine Deiminase (PAD)-PAD3 inhibitor 14b
PAD3 inhibitor 14b

Chemical Structure : PAD3 inhibitor 14b

CAS No.: 1671088-84-8

PAD3 inhibitor 14b (CAY10727)

货号: PC-25181Not For Human Use, Lab Use Only.

PAD3 inhibitor 14b is a potent and selective inhibitor of protein arginine deiminase PAD3 with kinact/KI value of 15600, ≥10-fold selectivity for PAD3 over PADs 1, 2, and 4.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PAD3 inhibitor 14b is a potent and selective inhibitor of protein arginine deiminase PAD3 with kinact/KI value of 15600, ≥10-fold selectivity for PAD3 over PADs 1, 2, and 4.

物理化学性质&存储条件

分子量 433.33
分子式 C21H22Cl2N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-chloro-N-(3-(1-((2'-chloro-[1,1'-biphenyl]-3-yl)methyl)-2,5-dioxoimidazolidin-4-yl)propyl)acetimidamide

参考文献

1. Jamali H, et al. J Am Chem Soc. 2015 Mar 18;137(10):3616-21.

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