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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Arginine Deiminase (PAD)-PAD-PF1
PAD-PF1

Chemical Structure : PAD-PF1

CAS No.:

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PAD-PF1

货号: PC-25182Not For Human Use, Lab Use Only.

PAD-PF1 is a small molecule potein arginine deiminase (PAD) inhibitor with binding KD of 2.82 uM and IC50 of 15.9 uM (PAD4).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PAD-PF1 is a small molecule potein arginine deiminase (PAD) inhibitor with binding KD of 2.82 uM and IC50 of 15.9 uM (PAD4).
PAD-PF1 binds to an allosteric site distinct from substrate and GSK147.

物理化学性质&存储条件

分子量 511.47
分子式 C25H31BrN6O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-amino-2-(1-(1-(5-bromopyridin-2-yl)-2,3-dimethyl-1H-pyrrolo[3,2-c]pyridin-4-yl)piperidin-4-yl)-1-(pyrrolidin-1-yl)ethan-1-one

参考文献

1. Dakin LA, et al. Nat Commun. 2025 May 16;16(1):4579.

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