Chemical Structure : PAC1 antagonist M65
CAS No.: 1872440-65-7
货号: PC-27327Not For Human Use, Lab Use Only.
PAC1 antagonist M65 is a truncated variant of Maxadilan and potent, specific antagonist of PACAP type 1 receptor (PACAP/VIP receptor 1, PVR1, PAC1 receptor), blocks the VIP-induced cAMP accumulation in cultured rat cortical neurons.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 2 mg | ¥1980 | In stock | |
| 5 mg | ¥3480 | In stock | |
| 10 mg | ¥5480 | In stock | |
| 25 mg | Get quote |
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PAC1 antagonist M65 is a truncated variant of Maxadilan and potent, specific antagonist of PACAP type 1 receptor (PACAP/VIP receptor 1, PVR1, PAC1 receptor), blocks the VIP-induced cAMP accumulation in cultured rat cortical neurons.
| 分子量 | 4823.53 | |
| 分子式 | C205H326N64O61S5 | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Cys-Asp-Ala-Thr-Cys-Gln-Phe-Arg-Lys-Ala-Ile-Asp-Asp-Cys-Gln-Lys-Gln-Ala-His-His-Ser-Asn-Val-Pro-Gly-Asn-Ser-Val-Phe-Lys-Glu-Cys-Met-Lys-Gln-Lys-Lys-Lys-Glu-Phe-Lys-Ala-NH2 (Disulfide bridge:Cys1-Cys5,Cys14-Cys32) |
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1. Uchida D, et al. Ann N Y Acad Sci. 1998 Dec 11;865:253-8.
2. Jansen-Olesen I, et al. Neuropeptides. 2014 Apr;48(2):53-64.
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