PAANIB-1

Chemical Structure : PAANIB-1

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货号: PC-38697Not For Human Use, Lab Use Only.

PAANIB-1 is a brain-penetrant PAAN/MIF nuclease inhibitor that prevents neurodegeneration that prevents neurodegeneration induced by α-syn PFF, AAV-α-syn overexpression, or MPTP intoxication in vivo.

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100 mg		Get quote

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生物&药学活性

PAANIB-1 is a brain-penetrant PAAN/MIF nuclease inhibitor that prevents neurodegeneration that prevents neurodegeneration induced by α-syn PFF, AAV-α-syn overexpression, or MPTP intoxication in vivo.

物理化学性质&存储条件

分子量	1169.34
分子式	C62H81FN6O15
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(12S,182S,4R,10S,13S,16S,E)-16-(tert-butoxymethyl)-4-(3,4-dimethoxyphenethyl)-55-fluoro-9,10,15,20,28,28-hexamethyl-13-phenyl-3,6,26-trioxa-9,12,15,20-tetraaza-1(2,1)-piperidina-18(1,2)-pyrrolidina-5(1,3)-benzenacyclotriacontaphan-23-ene-2,8,11,14,17,19,25,29,30-nonaone

参考文献

1. Hyejin Park, et al. Cell. 2022 May 5;S0092-8674(22)00467-6. doi: 10.1016/j.cell.2022.04.020.

PAANIB-1

生物&药学活性

物理化学性质&存储条件

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PAANIB-1

生物&药学活性

物理化学性质&存储条件

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