P2X7R antagonist A20 | P2X7 antagonist | Probechem Biochemicals

Chemical Structure : P2X7R antagonist A20

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P2X7R antagonist A20 (Compound 9q)

货号: PC-27099Not For Human Use, Lab Use Only.

P2X7R antagonist A20 (Compound 9q) is a potent, selective antagonist of ATP-gated channel P2X7 receptor (P2X7R) with IC50 of 18 nM (hP2X7), exhibits non-competitive negative allosteric mode of antagonism.

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生物&药学活性

P2X7R antagonist A20 (Compound 9q) is a potent, selective antagonist of ATP-gated channel P2X7 receptor (P2X7R) with IC50 of 18 nM (hP2X7), exhibits non-competitive negative allosteric mode of antagonism.

物理化学性质&存储条件

分子量	351.38
分子式	C18H13N3O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(quinolin-8-ylcarbamothioyl)benzo[d][1,3]dioxole-5-carboxamide

参考文献

1. Abid Mahmood, et al. Eur J Med Chem. 2022 Aug 5:238:114491.

2. Malik I, et al. Inflammopharmacology. 2026 Jun 17. doi: 10.1007/s10787-026-02297-0.

P2X7R antagonist A20 (Compound 9q)

生物&药学活性

物理化学性质&存储条件

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P2X7R antagonist A20 (Compound 9q)

生物&药学活性

物理化学性质&存储条件

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