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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Toll-like Receptor (TLR)-Oxymatrine
Oxymatrine

Chemical Structure : Oxymatrine

CAS No.: 16837-52-8

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Oxymatrine

货号: PC-24069Not For Human Use, Lab Use Only.

Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway, also is a TLR2 agonist that directly bind to toll-like receptor 2 (TLR2).

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500 mg ￥1280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway, also is a TLR2 agonist that directly bind to toll-like receptor 2 (TLR2).

物理化学性质&存储条件

分子量 264.37
分子式 C15H24N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(4S,41S,7aS,13aR,13bR)-10-Oxododecahydro-1H,5H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine 4(41H)-oxide

参考文献

1. Wu C, et al. Mol Med Rep. 2015 Jun;11(6):4129-34.

2. Ni C, et al. J Pharm Anal. 2025 Jan;15(1):101054.

3. Fan H, et al. Mediators Inflamm. 2009;2009:704706.

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