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首页-小分子抑制剂&激动剂-Others-Other Targets-Oxonic acid potassium
Oxonic acid potassium

Chemical Structure : Oxonic acid potassium

CAS No.: 2207-75-2

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Oxonic acid potassium (Potassium azaorotate;Potassium otastat;Potassium oxonate)

货号: PC-45315Not For Human Use, Lab Use Only.

An inhibitor of uricase that inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate catalyzed by pyrimidine phosphoribosyl-transferase in a different manner from allopurinol in cell-free extracts and intact cells in vitro..

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

An inhibitor of uricase that inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate catalyzed by pyrimidine phosphoribosyl-transferase in a different manner from allopurinol in cell-free extracts and intact cells in vitro.

物理化学性质&存储条件

分子量 195.1747
分子式 C4H2KN3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

H2O: ≥ 2 mg/mL; DMSO: < 1.9 mg/mL
Chemical Name/SMILES

1,3,5-Triazine-2-carboxylic acid, 1,4,5,6-tetrahydro-4,6-dioxo-, potassium salt (1:1)

参考文献

1. Shirasaka T, et al. Cancer Res. 1993 Sep 1;53(17):4004-9.

2. Eraranta A, et al. J Hypertens. 2008 Aug;26(8):1661-8.

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