Otenabant hydrochloride |CAS:686347-12-6 Probechem Biochemicals

Chemical Structure : Otenabant hydrochloride

CAS No.: 686347-12-6

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Otenabant hydrochloride (CP 945598 Hydrochloride;CP-945598 Hydrochloride;CP945598 Hydrochloride)

货号: PC-42724Not For Human Use, Lab Use Only.

A potent, and selective CB1 receptor antagonist with Ki of 0.7 nM/0.12 nM in binding and functional assays respectively.

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50 mg	￥3600	In stock
250 mg		Get quote

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生物&药学活性

A potent, and selective CB1 receptor antagonist with Ki of 0.7 nM/0.12 nM in binding and functional assays respectively; has low affinity (Ki=7600 nM) for human CB2 receptors; reverses cannabinoid agonist mediated responses, reduces food intake, and increases energy expenditure and fat oxidation in rodents.

Obesity

Phase 3 Discontinued

物理化学性质&存储条件

分子量	546.8792
分子式	C25H26Cl3N7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: 1 mg/mL
Chemical Name/SMILES	4-Piperidinecarboxamide, 1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)-, hydrochloride (1:1)

参考文献

1. Fulp A, et al. J Med Chem. 2012 Nov 26;55(22):10022-32.

2. Hadcock JR, et al. Biochem Biophys Res Commun. 2010 Apr 2;394(2):366-71.

3. Aronne LJ, et al. Obesity (Silver Spring). 2011 Jul;19(7):1404-14.

Otenabant hydrochloride (CP 945598 Hydrochloride;CP-945598 Hydrochloride;CP945598 Hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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询单

Otenabant hydrochloride (CP 945598 Hydrochloride;CP-945598 Hydrochloride;CP945598 Hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

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询单

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