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首页-小分子抑制剂&激动剂-GPCR-Luteinizing Hormone Receptor (LHR)-Org 42599
Org 42599

Chemical Structure : Org 42599

CAS No.: 501444-89-9

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Org 42599 (Org42599)

货号: PC-62038Not For Human Use, Lab Use Only.

Org 42599 is a cell-permeant, allosterically binding, small-molecule agonist of luteinizing hormone (LH) receptor that rescues the folding and cell surface expression mutant mutant human LH receptors A593P and S616Y (EC50=70.8 nM).

规格 价格 库存 数量
5 mg ￥2980 In stock
10 mg ￥4580 In stock
25 mg ￥7580 In stock
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纯度 & COA & 质检文件 纯度: 96.89% (HPLC) Select Batch:

生物&药学活性

Org 42599 is a cell-permeant, allosterically binding, small-molecule agonist of luteinizing hormone (LH) receptor that rescues the folding and cell surface expression mutant mutant human LH receptors A593P and S616Y (EC50=70.8 nM).

物理化学性质&存储条件

分子量 628.686
分子式 C26H31F3N6O5S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-amino-N-(tert-butyl)-2-(methylthio)-4-(3-(2-morpholinoacetamido)phenyl)thieno[2,3-d]pyrimidine-6-carboxamide 2,2,2-trifluoroacetate

参考文献

1. Newton CL, et al. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7172-6.

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