Org24598 | GlyT1 inhibitor | Probechem Biochemicals

Chemical Structure : Org24598

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Org24598 (Org 24598)

货号: PC-23734Not For Human Use, Lab Use Only.

Org24598 is a potent, selective glycine transporter 1 (GlyT1) inhibitor with pIC50 of 6.9 (GlyT-1b), shows negligible activity at hGlyT-2 (pIC50 <4.0).

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Org24598 is a potent, selective glycine transporter 1 (GlyT1) inhibitor with pIC50 of 6.9 (GlyT-1b), shows negligible activity at hGlyT-2 (pIC50 <4.0).
Org24598 is approximately 600× more potent than sarcosine.
Org24598 exhibits glycine uptake inhibition (GUI) activity in vivo.

物理化学性质&存储条件

分子量	367.37
分子式	C19H20F3NO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-(Methyl(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)amino)acetic acid

参考文献

1. Brown A, et al. Bioorg Med Chem Lett. 2001 Aug 6;11(15):2007-9.

Org24598 (Org 24598)

生物&药学活性

物理化学性质&存储条件

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Org24598 (Org 24598)

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物理化学性质&存储条件

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