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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phosphodiesterase (PDE)-Org-9935
Org-9935

Chemical Structure : Org-9935

CAS No.: 129425-83-8

Org-9935 (Org9935;Org 9935)

货号: PC-61338Not For Human Use, Lab Use Only.

Org-9935 (Org9935) is a potent, selective PDE3 inhibitor with IC50 of 50 nM.

规格 价格 库存 数量
25 mg Get quote
100 mg Get quote
500 mg Get quote
1 g Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Org-9935 (Org9935) is a potent, selective PDE3 inhibitor with IC50 of 50 nM.
    Org-9935 augments glucose-induced insulin release by rat isolated islets with EC50 of 20 uM.
    Org-9935 inhibits oocyte maturation in the naturally selected dominant follicle in rhesus macaques.

    物理化学性质&存储条件

    分子量 304.364
    分子式 C15H16N2O3S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6-(5,6-Dimethoxybenzo[b]thien-2-yl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone

    参考文献

    1. Dent G, et al. Br J Pharmacol. 1991 Jun;103(2):1339-46.

    2. Jensen JT, et al. Contraception. 2008 Apr;77(4):303-7.

    3. El-Metwally M, et al. Eur J Pharmacol. 1997 Apr 18;324(2-3):227-32.

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