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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-TRP Channel-Optovin
Optovin

Chemical Structure : Optovin

CAS No.: 348575-88-2

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Optovin (Photoactivated TRPA1 ligand)

货号: PC-43222Not For Human Use, Lab Use Only.

Optovin is a reversible photoactivated TRPA1 ligand that can be photoactivated by violet light, enables light-mediated neuronal excitation in treated animals with EC50 of 2 uM at 387 nm (violet), but not to 485 nm (blue), 560 nm (green) or longer wavelengths.

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10 mg ￥980 In stock
25 mg ￥1580 In stock
50 mg ￥2580 In stock
100 mg ￥4580 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Optovin is a reversible photoactivated TRPA1 ligand that can be photoactivated by violet light, enables light-mediated neuronal excitation in treated animals with EC50 of 2 uM at 387 nm (violet), but not to 485 nm (blue), 560 nm (green) or longer wavelengths.
Optovin shows activity on zebrafish, mouse neurons, and recombinant human protein, enables repeated photoactivation of motor behaviors in wild-type zebrafish and mice.

物理化学性质&存储条件

分子量 315.4132
分子式 C15H13N3OS2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
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Solubility

DMSO: ≥ 37 mg/mL
Chemical Name/SMILES

4-Thiazolidinone, 5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-

参考文献

1. Kokel D, et al. Nat Chem Biol. 2013 Apr;9(4):257-63.

2. Lu Y, et al. Anesthesiology. 2016 Dec;125(6):1171-1180.

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