Opigolix (ASP1707) | GnRH antagonist | Probechem Biochemicals

Chemical Structure : Opigolix

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Opigolix (ASP-1707, ASP1707)

货号: PC-61391Not For Human Use, Lab Use Only.

Opigolix (ASP-1707, ASP1707) is a potent gonadotrophin releasing hormone (GnRH) antagonist, significantly reduces endometriosis-associated pelvic pain.

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生物&药学活性

Opigolix (ASP-1707, ASP1707) is a potent gonadotrophin releasing hormone (GnRH) antagonist, significantly reduces endometriosis-associated pelvic pain.

ASP1707 suppresses the pituitary–gonadal axis, suggesting a therapeutic potential to ameliorate pain associated with endometriosis.

物理化学性质&存储条件

分子量	544.505
分子式	C25H19F3N4O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R)-N-{5-[3-(2,5-difluorophenyl)-2-(1,3-dihydro-2Hbenzimidazol-2-ylidene)-3-oxopropanoyl]-2-fluorobenzene-1-sulfonyl}-2-hydroxypropanimidamide

参考文献

1. D'Hooghe T, et al. Hum Reprod. 2019 May 1;34(5):813-823.

Opigolix (ASP-1707, ASP1707)

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Opigolix (ASP-1707, ASP1707)

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物理化学性质&存储条件

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