Onradivir (ZSP1273) | Influenza polymerase inhibitor | Probechem Biochemicals

Chemical Structure : Onradivir

加入收藏

货号: PC-73434Not For Human Use, Lab Use Only.

Onradivir (ZSP1273) is a potent inhibitor of the PB2 subunit of influenza A virus (IAV) polymerase.

获取报价单

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Onradivir (ZSP1273) is a potent inhibitor of the PB2 subunit of influenza A virus (IAV) polymerase.

Onradivir (ZSP1273) has btter half-maximal effective concentration (EC50) values oseltamivir.

Onradivir (ZSP1273) is sensitive for oseltamivir-resistant strains, baloxavir-resistant strains, and highly pathogenic avian influenza strains.

Onradivir (ZSP1273) effectively reduced IAV titres in a dose-dependent manner and maintained a high survival rate in mice.

分子量	440.455
分子式	C22H22F2N6O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3S)-3-((6-cyclopropyl-5-fluoro-2-(5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid

1. Yang Z, et al. Lancet Respir Med. 2025 Jun 6:S2213-2600(25)00046-3.