Ombitasvir | HCV NS5A inhibitor | Probechem Biochemicals

Chemical Structure : Ombitasvir

CAS No.: 1258226-87-7

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Ombitasvir (ABT-267, ABT267)

货号: PC-21352Not For Human Use, Lab Use Only.

Ombitasvir (ABT-267) is a potent, selective pan-genotypic inhibitor of HCV NS5A with EC50 of 1.7-19.3 pM against GT1a, -1b, -2a, -2b, -3a, -4a, and -5a and 366 pM against GT6a.

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50 mg	￥1780	In stock
100 mg	￥2880	In stock
200 mg	￥4280	In stock
1 g		Get quote

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生物&药学活性

Ombitasvir (ABT-267) is a potent, selective pan-genotypic inhibitor of HCV NS5A with EC50 of 1.7-19.3 pM against GT1a, -1b, -2a, -2b, -3a, -4a, and -5a and 366 pM against GT6a.
Ombitasvir (ABT-267) decreases HCV RNA up to 3.10 log10 IU/mL during 3-day monotherapy in treatment-naive HCV GT1-infected subjects.

物理化学性质&存储条件

分子量	894.13
分子式	C50H67N7O8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methyl ((S)-1-((S)-2-((4-((2S,5S)-1-(4-(tert-butyl)phenyl)-5-(4-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)phenyl)pyrrolidin-2-yl)phenyl)carbamoyl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate

参考文献

1. DeGoey DA, et al. J Med Chem. 2014 Mar 13;57(5):2047-57.

Ombitasvir (ABT-267, ABT267)

生物&药学活性

物理化学性质&存储条件

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Ombitasvir (ABT-267, ABT267)

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物理化学性质&存储条件

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