Olumacostat glasaretil | ACC inhibitor | Probechem Biochemicals

Chemical Structure : Olumacostat glasaretil

CAS No.: 1261491-89-7

加入收藏

Olumacostat glasaretil (DRM01)

货号: PC-45395Not For Human Use, Lab Use Only.

Olumacostat glasaretil (DRM01) is a small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC).

规格	价格	库存
5 mg	￥1180	In stock
10 mg	￥1880	In stock
25 mg	￥2980	In stock
50 mg	￥4880	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Olumacostat glasaretil (DRM01) is a small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC).
Olumacostat glasaretil (DRM01) inhibits de novo lipid synthesis in primary and transformed human sebocytes; reduces saturated and monounsaturated fatty acyl chains across lipid species, including di- and triacylglycerols, phospholipids, cholesteryl esters, and wax esters.
Olumacostat glasaretil (DRM01) significantly reduces hamster ear sebaceous gland size.
Olumacostat glasaretil (DRM01) a pro-drug of TOFA with enhance delivery in vivo.

物理化学性质&存储条件

分子量	481.6221
分子式	C26H43NO7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Furancarboxylic acid, 5-(tetradecyloxy)-, 2-[(2-ethoxy-2-oxoethyl)methylamino]-2-oxoethyl ester

参考文献

1. Bissonnette R, et al. J Am Acad Dermatol. 2017 Jan;76(1):33-39.

2. Hunt DW, et al. J Invest Dermatol. 2017 Jul;137(7):1415-1423.

3. Melnik BC. J Invest Dermatol. 2017 Jul;137(7):1405-1408.

Olumacostat glasaretil (DRM01)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Olumacostat glasaretil (DRM01)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.