Olesoxime (TRO 19622) |CAS:22033-87-0 Probechem Biochemicals

Chemical Structure : Olesoxime

CAS No.: 22033-87-0

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Olesoxime (TRO 19622, NSC21311)

货号: PC-62134Not For Human Use, Lab Use Only.

Olesoxime (TRO 19622) is a cholesterol-like compound that binds directly to two components of the mitochondrial permeability transition pore (mPTP): the voltage-dependent anion channel and TSPO (or PBR).

规格	价格	库存
10 mg	￥880	In stock
25 mg	￥1580	In stock
50 mg	￥2480	In stock
100 mg	￥3980	In stock
250 mg		Get quote

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生物&药学活性

Olesoxime (TRO 19622) is a cholesterol-like compound that binds directly to two components of the mitochondrial permeability transition pore (mPTP): the voltage-dependent anion channel and TSPO (or PBR).
Olesoxime rescues motor neurons from axotomy-induced cell death in neonatal rats and promoted nerve regeneration following sciatic nerve crush in vivio.
Olesoxime significantly reduces established mechano-allodynia and mechano-hyperalgesia.

物理化学性质&存储条件

分子量	399.65
分子式	C27H45NO
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Cholest-4-en-3-one oxime

参考文献

1. Bordet T, et al. J Pharmacol Exp Ther. 2007 Aug;322(2):709-20.

2. Schaller S, et al. J Pharmacol Exp Ther. 2010 Jun;333(3):696-706.

3. Sunyach C, et al. Neuropharmacology. 2012 Jun;62(7):2346-52.

4. Gouarné C, et al. Br J Pharmacol. 2013 Apr;168(8):1975-88.

Olesoxime (TRO 19622, NSC21311)

生物&药学活性

物理化学性质&存储条件

参考文献

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Olesoxime (TRO 19622, NSC21311)

生物&药学活性

物理化学性质&存储条件

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