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首页-抗体和重组蛋白-Biosimilar Antibody-Odronextamab
Odronextamab

Chemical Structure : Odronextamab

CAS No.: 1801338-64-6

Odronextamab (Anti-human CD20 CD3 bispecific mAb, human IgG4-Kappa; REGN19179)

货号: PC-Ab1035Not For Human Use, Lab Use Only.

Odronextamab (REGN1979) is a first-in-class, hinge-stabilized, fully human IgG4-based CD3 x CD20 bispecific antibody (bsAb), binds to CD20-expressing cells and CD3 on T cells, targeting CD20+ cells via T-cell-mediated cytotoxicity independent of T-cell receptor recognition. Odronextamab has demonstrated preliminary efficacy in relapsed/refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL)..

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1 mg ¥3580 In stock
5 mg ¥7580 In stock
10 mg ¥12800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Odronextamab (REGN1979) is a first-in-class, hinge-stabilized, fully human IgG4-based CD3 x CD20 bispecific antibody (bsAb), binds to CD20-expressing cells and CD3 on T cells, targeting CD20+ cells via T-cell-mediated cytotoxicity independent of T-cell receptor recognition. Odronextamab has demonstrated preliminary efficacy in relapsed/refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL).

物理化学性质&存储条件

分子量
分子式 Human IgG4-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

Odronextamab; REGN19179; REGN 19179; 1801338-64-6; CD20 CD3 bispecific; Anti-CD20 CD3

参考文献

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