OXi8006 | Tubulin inhibitor | Probechem Biochemicals

Chemical Structure : OXi8006

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OXi8006 (Oxi-8006)

货号: PC-23630Not For Human Use, Lab Use Only.

OXi8006 is a small molecule vascular disrupting agent and tubulin binding inhibior, inhibits tubulin assembly (IC50=1.1 uM) and shows cytotoxicity with GI50 of 3.45 nM against SK-OV-3 cells.

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生物&药学活性

OXi8006 is a small molecule vascular disrupting agent and tubulin binding inhibior, inhibits tubulin assembly (IC50=1.1 uM) and shows cytotoxicity with GI50 of 3.45 nM against SK-OV-3 cells.

物理化学性质&存储条件

分子量	463.49
分子式	C26H25NO7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2-(3-hydroxy-4-methoxyphenyl)-6-methoxy-1H-indol-3-yl)(3,4,5-trimethoxyphenyl)methanone

参考文献

1. Strecker TE, et al. Cancer Lett. 2015 Dec 1;369(1):229-41.

2. Macdonough MT, et al. Bioorg Med Chem. 2013 Nov 1;21(21):6831-43.

OXi8006 (Oxi-8006)

生物&药学活性

物理化学性质&存储条件

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OXi8006 (Oxi-8006)

生物&药学活性

物理化学性质&存储条件

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