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首页-小分子抑制剂&激动剂-Tyrosine Kinase-Syk-OXSI-2
OXSI-2

Chemical Structure : OXSI-2

CAS No.: 622387-85-3

OXSI-2 (OXSI 2)

货号: PC-21308Not For Human Use, Lab Use Only.

OXSI-2 is a putative and selective inhibitor of Syk with IC50 of 14 nM, inhibits convulxin-induced platelet functional responses.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

OXSI-2 is a putative and selective inhibitor of Syk with IC50 of 14 nM, inhibits convulxin-induced platelet functional responses.

物理化学性质&存储条件

分子量 353.40
分子式 C18H15N3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(1-Methyl-1H-indol-3-yl-methylene)-2-oxo-2, 3-dihydro-1H-indole-5-sulfonamide

参考文献

1. Bhavaraju K, et al. Eur J Pharmacol. 2008 Feb 12;580(3):285-90.

2. Buitrago L, et al. Blood. 2011 Nov 17;118(20):5631-40.

3. Law DA, et al. Blood. 1999;93:2645–2652.

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