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首页-小分子抑制剂&激动剂-GPCR-Orexin Receptor-OX2R agonist 1
OX2R agonist 1

Chemical Structure : OX2R agonist 1

CAS No.: 3015521-43-1

OX2R agonist 1

货号: PC-72582Not For Human Use, Lab Use Only.

OX2R agonist 1 is a potent, selective, small-molecule agonist of orexin receptor 2 (OX2R) with pEC50 of 8.28, >300-fold selectivity over OX1R.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    OX2R agonist 1 is a potent, selective, small-molecule agonist of orexin receptor 2 (OX2R) with pEC50 of 8.28, >300-fold selectivity over OX1R.

    物理化学性质&存储条件

    分子量 624.716
    分子式 C33H32N6O5S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3'-(N-(3-(2-(2-(2H-1,2,3-triazol-2-yl)benzamido)ethyl)phenyl)sulfamoyl)-4'-methoxy-N,N-dimethyl-[1,1'-biphenyl]-3-carboxamide

    参考文献

    1. Chuan Hong, et al. Nat Commun. 2021 Feb 5;12(1):815.

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