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首页-小分子抑制剂&激动剂-Others-Other Targets-OX03050
OX03050

Chemical Structure : OX03050

CAS No.: 1357581-47-5

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OX03050 (OX-03050, OX 03050)

货号: PC-60631Not For Human Use, Lab Use Only.

OX03050 is a potent, competitive squalene synthase inhibitor that upregulate the LDLR in mouse and human liver cell lines with EC50 of 26 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    OX03050 is a potent, competitive squalene synthase inhibitor that upregulate the LDLR in mouse and human liver cell lines with EC50 of 26 nM.
    OX03050 exhibits much-improved pharmacokinetic profile and shows in vivo efficacy compared with OX03771.

    物理化学性质&存储条件

    分子量 254.329
    分子式 C17H18O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-3-(4-styrylphenoxy)propan-1-ol

    参考文献

    1. Kerr AG, et al. J Pharmacol Exp Ther. 2017 Jun;361(3):417-428.

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