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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-CFTR-OSSK-674842
OSSK-674842

Chemical Structure : OSSK-674842

CAS No.: 2054944-80-6

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OSSK-674842 (OSSK-2, OSSK 674842)

货号: PC-70167Not For Human Use, Lab Use Only.

A novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    OSSK-674842 is a novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM.
    OSSK-674842 potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis.

    物理化学性质&存储条件

    分子量 457.122
    分子式 C16H15Br2N3O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-N'-(3,5-dibromo-2,4-dihydroxybenzylidene)-2-(p-tolylamino)acetohydrazide

    参考文献

    1. Cui G, et al. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L192-207.

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