OSI-420 |CAS:183320-51-6 Probechem Biochemicals

Chemical Structure : OSI-420

CAS No.: 183320-51-6

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OSI-420 (Desmethyl Erlotinib;CP-473420;OSI420;OSI 420;CP473420;CP 473420)

货号: PC-43436Not For Human Use, Lab Use Only.

OSI-420 (Desmethyl Erlotinib, CP-473420) is an active metabolite of erlotinib, which is a potent EGFR tyrosin kinase inhibitor for treatment of NSCLC..

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5 mg	￥1180	In stock
10 mg	￥1880	In stock
50 mg	￥3980	In stock
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OSI-420 (Desmethyl Erlotinib, CP-473420) is an active metabolite of erlotinib, which is a potent EGFR tyrosin kinase inhibitor for treatment of NSCLC.

物理化学性质&存储条件

分子量	415.87
分子式	C21H22ClN3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 4.2 mg/mL
Chemical Name/SMILES	Ethanol, 2-[[4-[(3-ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]-, hydrochloride (1:1)

参考文献

1. Broniscer A, et al. Clin Cancer Res. 2007 Mar 1;13(5):1511-5.

2. Meany HJ, et al. Cancer Chemother Pharmacol. 2008 Aug;62(3):387-92.

3. Togashi Y, et al. J Thorac Oncol. 2010 May;5(5):601-5.

4. Flaig TW, et al. Br J Cancer. 2010 Sep 7;103(6):796-801.

OSI-420 (Desmethyl Erlotinib;CP-473420;OSI420;OSI 420;CP473420;CP 473420)

生物&药学活性

物理化学性质&存储条件

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OSI-420 (Desmethyl Erlotinib;CP-473420;OSI420;OSI 420;CP473420;CP 473420)

生物&药学活性

物理化学性质&存储条件

参考文献

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