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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cyclin-dependent Kinase (CDK)-ON013100
ON013100

Chemical Structure : ON013100

CAS No.: 865783-95-5

ON013100 (ON-013100)

货号: PC-28695Not For Human Use, Lab Use Only.

ON013100 (ON-013100) is a small molecule mitotic inhibitor, potently inhibits the expression of CDK4, p53, mouse double minute 2 (MDM2), and Cyclin D, as well as increases cyclin B expression, alteres the growth and cell cycle status of MCL lines.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ON013100 (ON-013100) is a small molecule mitotic inhibitor, potently inhibits the expression of CDK4, p53, mouse double minute 2 (MDM2), and Cyclin D, as well as increases cyclin B expression, alteres the growth and cell cycle status of MCL lines.

物理化学性质&存储条件

分子量 394.44
分子式 C19H22O7S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-2-Methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)phenol

参考文献

1. Park IW, et al. Oncogene. 2007 Aug 16;26(38):5635-42.

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