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OMDM-1

Chemical Structure : OMDM-1

CAS No.: 616884-62-9

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OMDM-1 (OMDM1)

货号: PC-27604Not For Human Use, Lab Use Only.

OMDM-1 is a potent, selective inhibitor of anandamide cellular uptake (ACU) with Ki of 2.4 uM, inhibits anandamide transport.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

OMDM-1 is a potent, selective inhibitor of anandamide cellular uptake (ACU) with Ki of 2.4 uM, inhibits anandamide transport.
OMDM-1 shows poor affinity for either CB(1) (K(i)>5 uM) or CB(2) (K(i)>10 uM) receptors in rat brain and spleen membranes.
OMDM-1 also shows no activity at vanilloid receptors in the intracellular calcium assay carried out with intact cells over-expressing the human VR1 (EC(50)> or = 10 micro M), and no activity as inhibitors of FAAH in N18TG2 cell membranes.

物理化学性质&存储条件

分子量 431.66
分子式 C27H45NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-N-(1-Hydroxy-3-(4-hydroxyphenyl)propan-2-yl)oleamide

参考文献

1. Francavilla F, et al. Endocrinology. 2009 Oct;150(10):4692-700.

2. Fowler CJ, et al. Eur J Pharmacol. 2004 May 10;492(1):1-11.

3. Ortar G, et al. Biochem Pharmacol. 2003 May 1;65(9):1473-81.

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