Chemical Structure : OGG1 inhibitor O8
CAS No.: 350997-39-6
货号: PC-35807Not For Human Use, Lab Use Only.
OGG1 inhibitor O8 is a potent, selective inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 0.22 uM, displays no significant activity against other DNA Glycosylases (NEIL1, NTH1, Fpg, IC50>50 uM).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥880 | In stock | |
25 mg | ¥1380 | In stock | |
50 mg | ¥2180 | In stock | |
100 mg | ¥3680 | In stock | |
250 mg | Get quote |
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OGG1 inhibitor O8 is a potent, selective inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 0.22 uM, displays no significant activity against other DNA Glycosylases (NEIL1, NTH1, Fpg, IC50>50 uM).
分子量 | 261.12 | |
分子式 | C9H6Cl2N2OS | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
3,4-dichlorobenzo[b]thiophene-2-carbohydrazide |
1. Donley N, et al. ACS Chem Biol. 2015 Oct 16;10(10):2334-43. doi: 10.1021/acschembio.5b00452.
2. Visnes T, et al. Science. 2018 Nov 16;362(6416):834-839.
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