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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Oct3/4-OAC1
OAC1

Chemical Structure : OAC1

CAS No.: 300586-90-7

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OAC1 (OAC-1, Oct4-activating compound 1)

货号: PC-42966Not For Human Use, Lab Use Only.

Oct4-activating compound 1 (OAC1) is a small molecule Oct4-activating compound, enhances the iPSC reprogramming efficiency and accelerates the reprogramming process.

规格 价格 库存 数量
5 mg ￥580 In stock
10 mg ￥880 In stock
25 mg ￥1480 In stock
50 mg ￥2580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Oct4-activating compound 1 (OAC1) is a small molecule Oct4-activating compound, enhances the iPSC reprogramming efficiency and accelerates the reprogramming process.
OAC1 activates Oct4 and Nanog promoter-driven reporters in triplicate luciferase reporter assays, activates endogenous Oct4, Nanog, Sox2, and Tet1 expression.
OAC1 enhances reprogramming about fourfold at day 8 at 1 uM in iSF1 for the generation of mouse iPSCs.

物理化学性质&存储条件

分子量 237.2566
分子式 C14H11N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 40 mg/mL
Chemical Name/SMILES

Benzamide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-

参考文献

1. Li W, et al. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20853-8.

2. Huang X, et al. Leukemia. 2016 Jan;30(1):144-53.

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