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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-MEK (MAP2K)-Nuvrumetinib
Nuvrumetinib

Chemical Structure : Nuvrumetinib

CAS No.: 3079099-31-0

Nuvrumetinib (PAS-004, PAS004)

货号: PC-27483Not For Human Use, Lab Use Only.

Nuvrumetinib (PAS-004) is a potent, selective, next-generation macrocyclic MEK1/2 inhibitor.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Nuvrumetinib (PAS-004) is a potent, selective, next-generation macrocyclic MEK1/2 inhibitor.

物理化学性质&存储条件

分子量 570.32
分子式 C19H18F3IN2O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Spiro[1H,3H-8,2,1-benzoxathiazecine-3,1′-cyclopropane]-5,6-diol, 10,11-difluoro-12-[(2-fluoro-4-iodophenyl)amino]-4,5,6,7-tetrahydro-, 2,2-dioxide, (5R,6S)-

参考文献

1. Patent WO2025147503 A1 2025-07-10.

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