Nurr1 inverse agonist 31

Chemical Structure : Nurr1 inverse agonist 31

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货号: PC-20770Not For Human Use, Lab Use Only.

Nurr1 inverse agonist 31 is a small molecule inverse agonist of Nurr1 (NR4A2) with IC50 of 2.3 uM, mimicks the effect of Nurr1 silencing on interleukin-6 release from LPS-stimulated human astrocytes.

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50 mg		Get quote
100 mg		Get quote
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1 g		Get quote

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生物&药学活性

Nurr1 inverse agonist 31 is a small molecule inverse agonist of Nurr1 (NR4A2) with IC50 of 2.3 uM, mimicks the effect of Nurr1 silencing on interleukin-6 release from LPS-stimulated human astrocytes.

物理化学性质&存储条件

分子量	265.31
分子式	C17H15NO2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(C1=CN(C)C2=C1C=C(C3=CC=CC=C3)C=C2)OC

参考文献

1. Zaienne D, et al. J Med Chem. 2021 Oct 28;64(20):15126-15140.