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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Notum-Notum covalent inhibitor 2
Notum covalent inhibitor 2

Chemical Structure : Notum covalent inhibitor 2

CAS No.: 2758999-43-6

Notum covalent inhibitor 2

货号: PC-72825Not For Human Use, Lab Use Only.

Notum covalent inhibitor 2 is a potent, covalent Notum inhibitor with IC50 of 12 nM in OPTS assays, more poent than Notum covalent inhibitor 1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Notum covalent inhibitor 2 is a potent, covalent Notum inhibitor with IC50 of 12 nM in OPTS assays, more poent than Notum covalent inhibitor 1.

    物理化学性质&存储条件

    分子量 283.275
    分子式 C14H15F2NO3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2,2-difluoroethyl 4-(indolin-1-yl)-4-oxobutanoate

    参考文献

    1. Zhao Y, et al. J Med Chem. 2021 Aug 12;64(15):11354-11363.

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