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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aromatase-Norendoxifen
Norendoxifen

Chemical Structure : Norendoxifen

CAS No.: 1217237-98-3

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Norendoxifen

货号: PC-70132Not For Human Use, Lab Use Only.

Norendoxifen is an active metabolite of the selective estrogen receptor modulator (SERM) tamoxifen.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Norendoxifen is an active metabolite of the selective estrogen receptor modulator (SERM) tamoxifen.
    Norendoxifen is not a SERM, and instead has been found to act as a potent and selective competitive inhibitor of aromatase with Ki of 35 nM.

    物理化学性质&存储条件

    分子量 359.47
    分子式 C24H25NO2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (Z)-4-(1-(4-(2-aminoethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol

    参考文献

    1. Lu WJ, et al. Breast Cancer Res Treat. 2012 May;133(1):99-109.

    2. Lv W, et al. J Med Chem. 2015 Mar 26;58(6):2623-48.

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