Chemical Structure : Nivolumab
CAS No.: 946414-94-4
货号: PC-Ab1008Not For Human Use, Lab Use Only.
Nivolumab binds to the extracellular portion of human PD-1 (2.6 nM - Scatchard analysis and SPR) - the antibody also binds to cynomolgus PD-1 with a similar affinity (3.9 nM - SPR). The antibody does not bind to other immunoglobulin superfamily proteins such as CD28, CTLA-4, ICOS and BTLA. Nivolumab enhances immune response against various cancers. .
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Nivolumab binds to the extracellular portion of human PD-1 (2.6 nM - Scatchard analysis and SPR) - the antibody also binds to cynomolgus PD-1 with a similar affinity (3.9 nM - SPR). The antibody does not bind to other immunoglobulin superfamily proteins such as CD28, CTLA-4, ICOS and BTLA. Nivolumab enhances immune response against various cancers.
分子量 | ||
分子式 | Human IgG4 (S228P)-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Nivolumab; OPDIVO; BMS-936558; MDX-1106;CD279; programmed death-1; programmed death 1 ; PD1; PD 1; Programmed cell death protein 1; hPD-1; hPD1; hPD 1; BMS-936558; MDX-1106;ONO-4538 |
1. 1, Wolchok JD, et al. N Engl J Med. 2013 Jul 11;369(2):122-33. 2, Homet Moreno B, et al. Br J Cancer. 2015 Apr 28;112(9):1421-7. 3, Fu J, et al. Cancer Res. 2014 Aug 1;74(15):4042-52.
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