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Nitisinone

Chemical Structure : Nitisinone

CAS No.: 104206-65-7

Nitisinone (NTBC, Nitisone, SC0735)

货号: PC-21242Not For Human Use, Lab Use Only.

Nitisinone (NTBC, Nitisone, SC0735) is a potent, orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with IC50 of 173 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Nitisinone (NTBC, Nitisone, SC0735) is a potent, orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with IC50 of 173 nM.
Nitisinone (NTBC, Nitisone, SC0735) promotes tyrosine accumulation in a dose-dependent manner.
4-HPPD is a target for treating type I tyrosinemia and other diseases with defects in tyrosine catabolism.

物理化学性质&存储条件

分子量 329.23
分子式 C14H10F3NO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(2-nitro-4-(trifluoromethyl)benzoyl)cyclohexane-1,3-dione

参考文献

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