Nimesulide | COX-2 inhibitor | Probechem Biochemicals

Chemical Structure : Nimesulide

CAS No.: 51803-78-2

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Nimesulide (R805, R-805)

货号: PC-28646Not For Human Use, Lab Use Only.

Nimesulide (R705) is a non-steroid anti-inflammatory agent and selective COX-2 inhibitor with IC50s of 70 nM-70 μM in a time-dependent manner, shows no effect on COX-1 (IC50 >100 μM), exhibits potent anti-inflammatory, analgesic and antipyretic properties.

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生物&药学活性

Nimesulide (R805) is a non-steroid anti-inflammatory agent and selective COX-2 inhibitor with IC50s of 70 nM-70 μM in a time-dependent manner, shows no effect on COX-1 (IC50 >100 μM), exhibits potent anti-inflammatory, analgesic and antipyretic properties.

物理化学性质&存储条件

分子量	308.31
分子式	C13H12N2O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide

参考文献

1. Vago T, et al. Arzneimittelforschung. 1995 Oct;45(10):1096-8.

2. Werner MF, et al. Eur J Pharmacol. 2006 Aug 14;543(1-3):181-9.

Nimesulide (R805, R-805)

生物&药学活性

物理化学性质&存储条件

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Nimesulide (R805, R-805)

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物理化学性质&存储条件

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