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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-STAT-Niclosamide
Niclosamide

Chemical Structure : Niclosamide

CAS No.: 50-65-7

Niclosamide (BAY2353)

货号: PC-24028Not For Human Use, Lab Use Only.

Niclosamide (BAY2353) is an orally active antihelminthic agent, also is a STAT3 inhibitor with IC50 of 0.25 uM in HeLa cells.

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500 mg ¥280 In stock
1 g ¥380 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Niclosamide (BAY2353) is an orally active antihelminthic agent, also is a STAT3 inhibitor with IC50 of 0.25 uM in HeLa cells.

物理化学性质&存储条件

分子量 327.12
分子式 C13H8Cl2N2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide

参考文献

1. Xiaomei Ren, et al. ACS Med Chem Lett. 2010 Sep 7;1(9):454-9.

2. P Andrews, et al. Pharmacol Ther. 1982;19(2):245-95.

3. Kei Satoh, et al.Clin Cancer Res. 2016 Jul 15;22(14):3458-66.

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