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首页-小分子抑制剂&激动剂-Epigenetics-HDAC-Nexturastat A
Nexturastat A

Chemical Structure : Nexturastat A

CAS No.: 1403783-31-2

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Nexturastat A (HDAC6 inhibitor)

货号: PC-45044Not For Human Use, Lab Use Only.

Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM.

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5 mg ￥1580 In stock
10 mg ￥2480 In stock
25 mg ￥3980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM.
Nexturastat A displays >100-fold selectivity over other HDAC isozymes (600-fold relative to the inhibition of HDAC1).

物理化学性质&存储条件

分子量 341.4042
分子式 C19H23N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 56 mg/mL
Chemical Name/SMILES

Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy-

参考文献

1. Bergman JA, et al. J Med Chem. 2012 Nov 26;55(22):9891-9.

2. Miyake Y, et al. Nat Chem Biol. 2016 Sep;12(9):748-54.

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