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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Elastase-Neutrophil elastase inhibitor PD05
Neutrophil elastase inhibitor PD05

Chemical Structure : Neutrophil elastase inhibitor PD05

CAS No.: 3033318-13-4

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Neutrophil elastase inhibitor PD05 (PD05)

货号: PC-49231Not For Human Use, Lab Use Only.

Neutrophil elastase inhibitor PD05 is a potent selective and reversible human neutrophil elastase (HNE) inhibitor with Kd of 1.63 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Neutrophil elastase inhibitor PD05 is a potent selective and reversible human neutrophil elastase (HNE) inhibitor with Kd of 1.63 nM.
    Neutrophil elastase inhibitor PD05 reduces the alveolar collapse induced by neutrophil elastase in mouse model of COPD.

    物理化学性质&存储条件

    分子量 225.628
    分子式 C10H8ClNO3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(1-chloroethoxy)-4H-benzo[d][1,3]oxazin-4-one

    参考文献

    1. Sayantan Sengupta, et al. Eur J Pharmacol. 2022 Aug 8;931:175187.

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